Medicine information
उपयोग
TENELIGOLD M 500 by Steris Healthcare brings together two complementary blood sugar-lowering agents: Teneligliptin (20 mg) and Metformin Hydrochloride (500 mg). By pairing a novel third-generation DPP-4 inhibitor with a biguanide, this dual-combination therapy addresses multiple pathophysiological defects in type 2 diabetes—boosting glucose-dependent insulin secretion and improving peripheral insulin sensitivity. Key Uses & Clinical Benefits: Synergistic Glycemic Regulation: Effectively lowers both fasting and postprandial (post-meal) blood glucose levels, helping patients reach and maintain target HbA1c goals. Potent Incretin Enhancement: Teneligliptin (a long-acting DPP-4 inhibitor) prolongs the active life of naturally occurring incretin hormones (GLP-1 and GIP), boosting natural insulin secretion in response to meals while suppressing excessive glucagon release. Reduces Hepatic Glucose Output: Metformin decreases glucose production in the liver, reduces intestinal glucose absorption, and enhances peripheral tissue sensitivity to insulin. Low Risk of Hypoglycemia: Works primarily through glucose-dependent mechanisms, providing high therapeutic safety and a low risk of blood sugar drops when used as directed. Weight-Neutral Profile: Designed to deliver comprehensive blood sugar management without causing body weight gain, supporting long-term metabolic health. How TENELIGOLD M 500 Works: Teneligliptin (20 mg): Selectively inhibits the DPP-4 enzyme for extended 24-hour coverage, increasing mealtime insulin synthesis and curbing excess post-meal glucagon release. Metformin Hydrochloride (500 mg): Activates AMP-activated protein kinase (AMPK) in hepatic tissue to suppress gluconeogenesis and optimize cellular response to circulating insulin.
कैसे उपयोग करें
Take 1 tablet of TENELIGOLD M 500 once or twice daily with meals (preferably with breakfast and dinner) or strictly as prescribed by your physician. Taking the tablet with food helps reduce potential gastrointestinal upset associated with Metformin. Swallow the tablet whole with a glass of water. Do not crush, chew, or break the tablet.
भंडारण
Store in a cool, dry place away from direct sunlight, light, and moisture. Store at a controlled room temperature below 30°C. Keep out of reach and sight of children.
