Medicine information
Uses & overview
REMINIL AM 5/5 by Steris Healthcare brings together two complementary, evidence-based cardiovascular agents: Ramipril (5 mg) and Amlodipine (5 mg). Formulated for smooth, round-the-clock blood pressure regulation, this synergistic fixed-dose combination addresses hypertension through dual vascular pathways—inhibiting vasoconstrictive hormone production while directly relaxing arterial smooth muscle to reduce systemic vascular resistance and cardiac workload. Key Ingredients & Clinical Benefits: Ramipril (5 mg): A potent Angiotensin-Converting Enzyme (ACE) inhibitor that blocks the conversion of angiotensin I to the potent vasoconstrictor angiotensin II. It relaxes vascular walls, reduces aldosterone secretion, lowers blood pressure, and provides vital cardioprotective and renoprotective benefits. Amlodipine (5 mg): A long-acting dihydropyridine Calcium Channel Blocker (CCB) that selectively inhibits calcium ion influx into vascular smooth muscle and cardiac cells. It induces arterial vasodilation, decreases peripheral vascular resistance, and improves coronary blood flow. Key Uses & Clinical Benefits: Synergistic 24-Hour Blood Pressure Control: Provides smooth, continuous blood pressure reduction over a full 24-hour cycle when monotherapy fails to achieve optimal target levels. Dual Mechanism of Action: Combines systemic vasodilation with neurohormonal blockade for superior clinical efficacy and vascular health. Target Organ Protection: Reduces long-term hypertensive damage to microvascular structures in the heart, kidneys, and brain, lowering the risk of stroke, heart attack, and renal impairment. Mitigates Peripheral Edema: The ACE inhibitor component (Ramipril) helps counteract venodilatory imbalance, reducing the incidence of ankle swelling (pedal edema) commonly associated with Amlodipine monotherapy. Enhanced Pill Adherence: Combines two essential daily cardiovascular medications into a single, convenient fixed-dose tablet, improving long-term patient compliance.
How to use
Take 1 tablet of REMINIL AM 5/5 once daily, with or without food (preferably in the morning), or strictly as prescribed by your cardiologist or physician. Swallow the tablet whole with a glass of water. Do not crush, chew, or break the tablet. Try to take your dose at the same time every day to maintain steady blood pressure control. Do not stop taking the medication abruptly without medical guidance.
Storage
Store in a cool, dry, and dark place away from direct sunlight, heat, and moisture. Store at a controlled room temperature below 30°C. Keep out of reach and sight of children.
