Medicine information
Uses & overview
ST- GLIPTIN DAPA 100/10 by Steris Healthcare brings together two powerful, complementary anti-diabetic agents: Sitagliptin Phosphate (100 mg) and Dapagliflozin (10 mg). By pairing a DPP-4 inhibitor with an SGLT2 inhibitor, this dual-action formula targets type 2 diabetes through two distinct, non-overlapping pathways—enhancing physiological insulin secretion and naturally eliminating excess glucose through urine. Key Uses & Clinical Benefits: Comprehensive Glycemic Regulation: Effectively lowers both fasting and postprandial (post-meal) blood glucose levels, helping patients reach and maintain target HbA1c levels. Incretin Enhancement: Sitagliptin (a DPP-4 inhibitor) prolongs the active life of incretin hormones (GLP-1 and GIP), boosting natural insulin release in response to meals while suppressing glucagon secretion. Glucose Excretion via Kidneys: Dapagliflozin (an SGLT2 inhibitor) blocks glucose reabsorption in the renal tubules, allowing excess blood sugar to be naturally excreted through urine. Cardiovascular & Renal Protection: Dapagliflozin provides extra organ-protective benefits, reducing the risk of heart failure hospitalizations and helping slow the progression of chronic kidney disease (CKD). Low Risk of Hypoglycemia & Weight-Neutral Profile: Works through glucose-dependent mechanisms, resulting in a low risk of low blood sugar when used as prescribed, while supporting healthy weight management. How ST- GLIPTIN DAPA 100/10 Works: Sitagliptin Phosphate (100 mg): Prevents the enzymatic breakdown of incretin hormones by DPP-4, increasing insulin production and lowering excess glucagon levels. Dapagliflozin (10 mg): Inhibits sodium-glucose co-transporter 2 (SGLT2) in the proximal renal tubules of the kidneys, preventing filtered glucose from re-entering the bloodstream.
How to use
Take 1 tablet of ST- GLIPTIN DAPA 100/10 once daily in the morning, with or without food, or as directed by your physician. Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet. Maintain adequate fluid intake throughout the day to support healthy kidney function.
Storage
Store in a cool, dry place away from direct sunlight, light, and moisture. Maintain at a controlled room temperature below 30°C. Keep out of reach and sight of children.
