Medicine information
Uses & overview
TENELIGOLD M 1000 by Steris Healthcare brings together two complementary blood sugar-lowering agents: Teneligliptin (20 mg) and Metformin Hydrochloride (1000 mg). By combining a novel, long-acting DPP-4 inhibitor with a higher dose of biguanide, this dual-action formulation targets type 2 diabetes through two distinct pathways—enhancing glucose-dependent insulin secretion and significantly improving peripheral insulin sensitivity. Key Uses & Clinical Benefits: Maximum Dual Glycemic Regulation: Effectively lowers both fasting and postprandial (post-meal) blood glucose levels, helping patients reach and sustain target HbA1c goals. Potent Incretin Enhancement: Teneligliptin (a third-generation DPP-4 inhibitor) prolongs the active life of naturally occurring incretin hormones (GLP-1 and GIP), boosting natural mealtime insulin release while suppressing excessive glucagon secretion. Reduces Hepatic Glucose Output: Metformin decreases glucose synthesis in the liver, lowers intestinal glucose absorption, and enhances peripheral tissue sensitivity to circulating insulin. Low Risk of Hypoglycemia: Works primarily through glucose-dependent mechanisms, providing high therapeutic safety and a low risk of low blood sugar spikes when used as directed. Weight-Neutral Profile: Offers comprehensive blood sugar management without causing body weight gain, supporting long-term metabolic health. How TENELIGOLD M 1000 Works: Teneligliptin (20 mg): Selectively inhibits the DPP-4 enzyme for extended 24-hour coverage, raising active incretin hormone levels to stimulate pancreatic insulin output and inhibit inappropriate glucagon secretion. Metformin Hydrochloride (1000 mg): Activates AMP-activated protein kinase (AMPK) in hepatic tissue to suppress gluconeogenesis and optimize cellular glucose uptake in skeletal muscle.
How to use
Take 1 tablet of TENELIGOLD M 1000 twice daily with meals (preferably with breakfast and dinner) or strictly as prescribed by your physician. Taking the medication with food helps minimize potential gastrointestinal discomfort associated with Metformin. Swallow the tablet whole with a glass of water. Do not crush, chew, or break the tablet.
Storage
Store in a cool, dry place away from direct sunlight, light, and moisture. Store at a controlled room temperature below 30°C. Keep out of reach and sight of children.
